Mouse Monoclonal Antibody to SMAD530150
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD5 is required for normal development of the cardiovascular system in vivo; lack of the SMAD5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of SMAD5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Rat
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human SMAD5 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=549
Reference: 1. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3927-32. ; 2. Nat Cell Biol. 2008 May;10(5):567-74.
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