Mouse Monoclonal Antibody to PDK1
30154
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Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. (provided by RefSeq). Tissue specificity: Expressed predominantly in the heart.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Monkey; Rat
Clone: 4A11;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human PDK1 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
MW: 44kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=553
Reference: 1. Nat Cell Biol. 2008 Feb;10(2):127-37. ; 2. Blood. 2008 Apr 1;111(7):3723-34. ; 3. J Biol Chem. 2007 Apr 20;282(16):12272-89.
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