Mouse Monoclonal Antibody to MSX1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Drosophila,muscle segment (msh) homolog 1,homeo domain encoding gene,inhibiting MYOD1 expression,highly expressed in dental mesenchyme during critical bud stage,involved in epithelial-mesenchymal signaling in many organs,and in the pathogenesis of cleft lip and palate,interacting with MSX2 in mouse limb bud patterning .This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition.Tissue specificity: Expressed in the developing nail bed mesenchyme.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5D11;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human MSX1 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 31kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=596
Reference: 1. Zhonghua Kou Qiang Yi Xue Za Zhi. 2008 Mar;43(3):157-9. ; 2. Endocr Pathol. 2008 Spring;19(1):54-61.

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