Mouse Monoclonal Antibody to GRK230199
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse; Rat; Monkey
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human GRK2 expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=598
Reference: 1. Mol Biol Cell. 2008 Jul;19(7):2973-83. ; 2. Biochemistry. 2009 May 26;48(20):4285-93.
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