Mouse Monoclonal Antibody to PODXL

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. (provided by RefSeq)Tissue specificity: Glomerular epithelium cell (podocyte)
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5D4;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human PODXL expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 49kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=604
Reference: 1. Blood. 2009 Jan 22;113(4):816-26. ; 2. Am J Physiol Cell Physiol. 2009 Mar;296(3):C505-13.

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