Figure 1: Western blot analysis using PINCH mAb against human PINCH (AA: 87-249) recombinant protein. (Expected MW is 44.2 kDa)

Mouse Monoclonal Antibody to PINCH

30241

Regular price $341.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5G7;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human PINCH expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 37kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=640
Reference: 1. J Biol Chem. 2009 Feb 27;284(9):5836-44. ; 2. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20677-82.

Note: Highly recommend to send quote request for product availability and estimated shipping charge