Figure 1: Western blot analysis using LMNA mAb against human LMNA (AA: 212-477) recombinant protein. (Expected MW is 56.3 kDa)
Mouse Monoclonal Antibody to LMNA

Mouse Monoclonal Antibody to LMNA

30247

Regular price $341.00 $290.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse; Rat
Clone: 4E7;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human LMNA expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 74kDa
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=646
Reference: 1. Muscle Nerve. 2010 Jan;41(1):85-91. ; 2. Endocrine. 2009 Dec;36(3):518-23.