Mouse Monoclonal Antibody to C-CBL30250
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse; Rat
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human C-CBL expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=649
Reference: 1. Blood. 2009 Aug 27;114(9):1859-63. ; 2. Cell Res. 2009 Aug;19(8):950-61. ; 3. Nature. 2009 Aug 13;460(7257):904-8.
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