Mouse Monoclonal Antibody to PGC-1alpha

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. 
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 1G8;
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human PGC-1alpha expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 91kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=664
Reference: 1. Diabetes Res Clin Pract. 2009 Dec;86(3):168-72. ; 2.Cell Metab. 2009 Sep;10(3):189-98. ;

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