Figure 1: Western blot analysis using KCNQ1 mAb against human KCNQ1 (AA: 229-347) recombinant protein. (Expected MW is 74.7 kDa)
Mouse Monoclonal Antibody to KCNQ1

Mouse Monoclonal Antibody to KCNQ1

30297

Regular price $341.00 $290.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. 
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5E12;
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human KCNQ1 expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
MW: 95kDa
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=696
Reference: 1. Biochem Biophys Res Commun. 2009 May 29;383(2):206-9.  ; 2. J Biol Chem. 2009 Jun 12;284(24):16452-62.  ;