Mouse Monoclonal Antibody to PPP2R4

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 4D9;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human PPP2R4 expressed in E. Coli. ;
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 41kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=707
Reference: 1. Stem Cells. 2010 May;28(5):874-84. ; 2. Mol Biol Cell. 2010 Mar 15;21(6):1140-52.

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