Mouse Monoclonal Antibody to CCL2

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse; Monkey
Clone: 2D8;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human CCL2 expressed in E. Coli. ;
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 11kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=750
Reference: J Cereb Blood Flow Metab. 2010 Mar;30(3):459-73. ; Prostate. 2010 Mar 1;70(4):433-42. ;

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