Mouse Monoclonal Antibody to TGFb1
30383
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$341.00
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Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 7F6;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human TGFb1 (AA: 62-195) expressed in E. Coli. ; ;
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 44.3kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=782
Reference: 1.Cell. 2011 Oct 28;147(3):565-76. ; 2.Kobe J Med Sci. 2011 May 11;56(6):E242-52. ;
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