Mouse Monoclonal Antibody to EGFR mutant
30486A
Regular price
$341.00
You Pay
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5G9B5;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human EGFR mutant (AA: 693-893) expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 175kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3456
Reference: 1. J Immunol. 2012 Dec 1;189(11):5230-9. ; 2. J Biol Chem. 2012 Oct 12;287(42):35201-11. ;
Note: Highly recommend to send quote reqeust for estimated shipping charge including ice