Mouse Monoclonal Antibody to IL3RA

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. ; ; ; ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 8E11C5;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human IL3RA (AA: 200-305) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 43.3kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3477
Reference: 1. Am J Clin Pathol. 2011 Oct;136(4):625-30. ; 2. Chin Med J (Engl). 2010 Aug 5;123(15):2034-7. ;

Note: Highly recommend to send quote request for product availability and estimated shipping charge