
Mouse Monoclonal Antibody to GPNMB
30520
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$341.00
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Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 7C10E5;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 64kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3481
Reference: 1. Prostate. 2012 Sep 15;72(13):1431-42. ; 2. Melanoma Res. 2010 Jun;20(3):184-90. ;
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