Mouse Monoclonal Antibody to PAPLN
30557
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$341.00
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Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Papilin is an extracellular matrix glycoprotein involved in, thin matrix layers during gastrulation, matrix associated with wandering, phagocytic hemocytes, basement membranes and space-filling matrix during Drosophila development.Determination of its cDNA sequence led to the identification of Caenorhabditis and mammalian papilins. A distinctly conserved 'papilin cassette' of domains at the amino-end of papilins is also the carboxyl-end of the ADAMTS subgroup of secreted, matrix-associated metalloproteinases; this cassette contains one thrombospondin type 1 (TSR) domain, a specific cysteine-rich domain and several partial TSR domains. In vitro, papilin non-competitively inhibits procollagen N-proteinase, an ADAMTS metalloproteinase. ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5F2D10;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human PAPLN (AA: 766-870) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 137.7kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3518
Reference: 1. Int J Biochem Cell Biol. 2004 Jun; 36(6):1079-84. ; 2. Development. 2000 Dec;127(24):5475-85. ;
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