Mouse Monoclonal Antibody to GABBR230604
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence. ; ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of human GABBR2 (AA: 319-483) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide.
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3565
Reference: 1. J Biol Chem. 2007 Feb 9;282(6):4162-71. ; 2. Genomics. 1999 Mar 15;56(3):288-95. ;
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