Mouse Monoclonal Antibody to PIK3CG

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 4B5D2;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human PIK3CG (AA: 1-100) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide.
MW: 126.5kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3648
Reference: 1. Lab Invest. 2013 May;93(5):566-76.; 2. Biochem Biophys Res Commun. 2011 Jan 28;404(4):968-73.

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