Figure 1: Western blot analysis using TCL1A mAb against human TCL1A (AA: 10-104) recombinant protein. (Expected MW is 37.3 kDa)
Mouse Monoclonal Antibody to TCL1A

Mouse Monoclonal Antibody to TCL1A

30715

Regular price $341.00 $290.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 2E3A5;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human TCL1A (AA: 10-104) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide.
MW: 13.5kDa
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3676
Reference: 1. Blood. 2012 Aug 23;120(8):1613-23.; 2. Histopathology. 2010 Jul;57(1):152-7.