Mouse Monoclonal Antibody to PDGFRA

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 8E12F2;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human PDGFRA (AA: 361-528) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide.
MW: 122.7kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3689
Reference: 1. Stem Cells Dev. 2013 Jul 1;22(13):1932-43.; 2. Cancer Biol Ther. 2012 Dec;13(14):1384-9.

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