Figure 1: Western blot analysis using ANPEP mAb against human ANPEP (AA: Extra(781-967)) recombinant protein. (Expected MW is 47.4 kDa)
Mouse Monoclonal Antibody to ANPEP

Mouse Monoclonal Antibody to ANPEP

30732

Regular price $341.00 $290.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 1C7D7;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human ANPEP (AA: Extra(781-967)) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide.
MW: 110kDa
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3693
Reference: 1. Br J Cancer. 2013 Feb 5;108(2):420-8. ; 2. Ann Surg Oncol. 2012 Jul;19 Suppl 3:S539-48.