Mouse Monoclonal Antibody to HH3

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse
Clone: 4E9B11;
Isotype: Mouse IgG1
Immunogen: Synthesized peptide of human HH3 (AA: ARTKQTAR(AcK)STG-C).
Formulation: Purified antibody in PBS with 0.05% sodium azide.
MW: 15.5kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3699
Reference: 1. J Cell Biochem. 2009 Oct 1;108(2):400-7.; 2. Trends Biochem Sci. 2005 Jul;30(7):357-9.

Note: Highly recommend to send quote reqeust for estimated shipping charge including ice