Mouse Monoclonal Antibody to CBX1
30802
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$341.00
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Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 4D7B8;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human CBX1 (AA: 1-185) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 21.4kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3952
Reference: 1.Endocr Relat Cancer. 2010 May 18;17(2):455-67. ; 2.Am J Pathol. 2011 Feb;178(2):672-8. ;
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