Mouse Monoclonal Antibody to GAD2

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5D9G12;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human GAD2 (AA: 1-100) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 65.4kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3992
Reference: 1.Histopathology. 2013 Sep;63(3):334-42. ; 2.Biol Psychiatry. 2012 Nov 1;72(9):734-43.;

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