Mouse Monoclonal Antibody to PDGFRB

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse
Clone: 2G7B7;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human PDGFRB (AA: 33-133) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 124kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4002
Reference: 1.J Cell Sci. 2012 May 1;125(Pt 9):2276-87. ; 2.J Cell Physiol. 2012 May;227(5):2089-96.;

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