Figure 1:Immunofluorescence analysis of HeLa cells using PMS2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-

Mouse Monoclonal Antibody to PMS2

30863

Regular price $341.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 1E9D11;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human PMS2 (AA: 748-851) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 95.8kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4012
Reference: 1.J Med Genet. 2013 Aug;50(8):552-63. ; 2.Hum Mutat. 2010 May;31(5):552-60.;

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