Mouse Monoclonal Antibody to DDX20

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: 1/200 - 1/1000; FCM:
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 7B2B1;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human DDX20 (AA: 725-824) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 92.2kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4047
Reference: 1.J Clin Invest. 2014 Sep;124(9):3807-24. ; 2.J Biol Chem. 1999 Jul 2;274(27):19136-44.;

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