Mouse Monoclonal Antibody to HIST2H3C(27Ac)

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.;
Application: ELISA: 1/10000; WB: ; IHC: 1/200 - 1/1000; ICC: ; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 2D7B3;
Isotype: Mouse IgG1
Immunogen: Synthesized peptide of human HIST2H3C (AA: ATKAARK(Ac)SAPATGGV) .
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 15.4kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4049
Reference: 1.Cell Cycle. 2014;13(3):440-52. ; 2.Cell Cycle. 2009 Jun 1;8(11):1747-53.;

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