Mouse Monoclonal Antibody to LEF1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: ; FCM:
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 3G5F9;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human LEF1 (AA: 33-138) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 44.2kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4082
Reference: 1.Cancer Invest. 2014 Aug;32(7):368-74. ; 2.BMC Gastroenterol. 2012 May 28;12:53.;

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