Mouse Monoclonal Antibody to CBX5

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM:
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse
Clone: 2H4E9;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human CBX5 (AA: 1-191) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 22.2kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4085
Reference: 1.Mol Carcinog. 2011 Aug;50(8):601-13. ; 2.J Mol Biol. 2013 Jan 9;425(1):54-70.;

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