Mouse Monoclonal Antibody to JARID2

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 7H1B3;
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of human JARID2 (AA: 1097-1246) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 139kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4097
Reference: 1.PLoS One. 2014 Dec 26;9(12):e115684. ; 2.Am J Hematol. 2012 Mar;87(3):245-50.;

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