Mouse Monoclonal Antibody to CDH11

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 4E12G10;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human CDH11 (AA: 468-617) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 88kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4148
Reference: 1.Arthritis Rheumatol. 2014 Apr;66(4):1010-21. ; 2.Mol Cancer Res. 2012 Mar;10(3):293-304. ;

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