Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Mouse Monoclonal Antibody to SEC31A

31004

Regular price $341.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: ; FCM:
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5D12C6;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human SEC31A (AA: 429-571) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 133kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4154
Reference: 1.J Biol Chem. 2015 Feb 20;290(8):4981-93. ; 2.Blood. 2011 Apr 14;117(15):4056-64. ;

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