Mouse Monoclonal Antibody to SYN1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: 1/200 - 1/1000; FCM:
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse; Rat
Clone: 7B1D9;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human SYN1 (AA: 362-511) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 74.1kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4164
Reference: 1.Synapse. 2012 Nov;66(11):979-83. ; 2.J Neurosci Res. 2009 Aug 1;87(10):2255-63.;

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