Mouse Monoclonal Antibody to MAPK10

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM:
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Rat
Clone: 2B10H12;
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of human MAPK10 (AA: 180-329) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 52.6kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4188
Reference: 1.J Diabetes Res. 2014;2014:814854. ; 2.Pathol Int. 2011 Jan;61(1):52-4.;

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