Mouse Monoclonal Antibody to PTPN14

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 2B3H7;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human PTPN14 (AA: 896-1169) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 135.3kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4198
Reference: 1.Oncogene. 2013 Apr 18;32(16):2087-95. ; 2.PLoS One. 2013 Apr 16;8(4):e61916. ;

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