Mouse Monoclonal Antibody to C3C

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 4C6A8;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human C3C (AA: 1521-1649) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 187.1kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4205
Reference: 1.Blood. 2015 Apr 9;125(15):2359-69. ; 2.Mediators Inflamm. 2013;2013:716902.;

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