Mouse Monoclonal Antibody to DNTT

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM:
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 4B10C3;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human DNTT (AA: 52-192) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 58.5kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4224
Reference: 1.Mod Pathol. 2013 Oct;26(10):1338-45. ; 2.Haematologica. 2006 Aug;91(8):1139-40.;

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