Mouse Monoclonal Antibody to HLA-DRA

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: 1/100 - 1/500; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 1C11A5;
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human HLA-DRA (AA: 26-254) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 58.8kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4263
Reference: 1.Int J Immunogenet. 2014 Dec;41(6):508-11. ; 2.Am J Rhinol Allergy. 2012 Jan-Feb;26(1):12-7. ;

Note: Highly recommend to send quote reqeust for estimated shipping charge including ice