Mouse Monoclonal Antibody to NR1I2

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 6H11D8;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human NR1I2 (AA:1-142) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 9.8kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4267
Reference: 1.Int J Mol Sci. 2014 Sep 29;15(10):17457-68. ; 2.J Periodontal Res. 2012 Apr;47(2):174-9. ;

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