Mouse Monoclonal Antibody to TCF4

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described. ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 7B1B3;
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human TCF4 (AA: 518-667) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 147kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4299
Reference: 1.J Psychiatr Res. 2015 Oct;69:95-101. ; 2.Haematologica. 2014 Dec;99(12):e257-9.;

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