Mouse Monoclonal Antibody to APBA2

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: 1/50 - 1/200; FCM:
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 1C12A4;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human APBA2 (AA: 15-158) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 63.4kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4307
Reference: 1.Neuroreport. 2012 Feb 15;23(3):146-51. ; 2.Autism Res. 2009 Dec;2(6):359-64. ;

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