Mouse Monoclonal Antibody to ATF4

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: ; FCM:
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 2A6F12;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human ATF4 (AA: 212-351) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 33.8kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4312
Reference: 1.Cell. 2014 Aug 28;158(5):1159-72. ; 2.Tumour Biol. 2014 Jan;35(1):765-71.;

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