Mouse Monoclonal Antibody to Phospho-4E-BP1 (Ser65)31174
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Application: ELISA: 1/10000; WB: N/A; ICC: 1/100 - 1/500; FCM: 1/200 - 1/400; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Synthesized peptide of human Phospho-4E-BP1 (Ser65).
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4324
Reference: 1.Sci Signal. 2015 Nov 17;8(403):ra116.2.Oncotarget. 2015 Sep 15;6(27):24092-104.
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