Mouse Monoclonal Antibody to RUNX3

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/50 - 1/250; FCM: 1/200 - 1/400; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 7E2B8
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human RUNX3 (AA: 294-429) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 44.4kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4357
Reference: 1.Genet Mol Res. 2015 Dec 1;14(4):15505-10.2.J Pathol. 2015 Dec;237(4):520-31.

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