Mouse Monoclonal Antibody to CHRNA6

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/100 - 1/500; FCM: 1/200 - 1/400; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5B6G8
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human CHRNA6 (AA: 26-239) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 57kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4376
Reference: 1.Mol Brain. 2014 May 2;7:35. 2.Mol Psychiatry. 2010 Jan;15(1):6-8.

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