Mouse Monoclonal Antibody to ATG531270
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/100 - 1/500; FCM: 1/200 - 1/400; IHC: N/A
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human ATG5 (AA: 144-275) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4420
Reference: 1.PLoS One. 2014 Oct 17;9(10):e110293.2.Sci Transl Med. 2013 Sep 11;5(202):202ra123.
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