Mouse Monoclonal Antibody to GRIN2A

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: 1/200 - 1/400; IHC: N/A
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 3G10F9
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human GRIN2A (AA: extra 23-165) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 165.3kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4429
Reference: 1.PLoS Genet. 2014 Nov 20;10(11):e1004788.2.PLoS One. 2014 Jun 10;9(6):e99294.

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