Mouse Monoclonal Antibody to GLRB

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400; IHC: N/A
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 3B8A8
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human GLRB (AA: extra 23-160) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 56.1kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4439
Reference: 1.Hum Mol Genet. 2013 Mar 1;22(5):927-40.2.Clin Genet. 2012 May;81(5):479-84.

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